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| 产品编号 | 产品名称 | 产品包装 | 产品价格 |
| P2523-10μg | Recombinant Human CMPK1 (His-Tag) | 10μg | 228.00元 |
| P2523-50μg | Recombinant Human CMPK1 (His-Tag) | 50μg | 668.00元 |
| P2523-200μg | Recombinant Human CMPK1 (His-Tag) | 200μg | 1698.00元 |
| P2523-1mg | Recombinant Human CMPK1 (His-Tag) | 1mg | 4998.00元 |
| Species | Gene ID | Accession | Source | Length | MW | Tag |
| Human | 51727 | P30085 | E. coli | 204aa | 23kDa | N-His-Tag |
| 蛋白信息(About this protein) | |
| 名称(Name) | Recombinant Human CMPK1 (His-Tag); 重组人UMP-CMP激酶 |
| 别名(Synonyms) | CK; CMK; CMPK; UMK; UMPK; UMP-CMP kinase; Deoxycytidylate kinase; Nucleoside-diphosphate kinase; Uridine monophosphate/cytidine monophosphate kinase |
| 产品简介 (Background) |
Beyotime's Recombinant Human CMPK1 (His-Tag) was expressed in E. coli and purified, which contains the full length of human CMPK1 (Pro2-Gly196) with His-Tag fusion at the N-terminus. CMPK1, also known as UMP-CMP kinase is part of the nucleotide metabolism network, which is responsible for the synthesis and interconversion of nucleotides that are essential for cellular activities. This enzymatic activity is of importance in the de novo biosynthesis of pyrimidine nucleotides, representing a critical step in the synthesis of essential cellular components. During this process, CMPK1 preferentially selects uridine monophosphate (UMP) and cytidine monophosphate (CMP) as phosphate receptors. Additionally, CMPK1 exhibits extensive nucleoside diphosphate kinase activity, demonstrating its versatility in catalyzing the transfer of phosphate groups between different nucleoside diphosphates. The multifaceted functions of CMPK1 reveal its pivotal role in cellular nucleotide metabolism and its potential impact on various cellular processes [1-3]. |
| 产品用途 (Applications) |
Study of nucleotide metabolism, enzymatic activity and cellular processes that rely on nucleotide biosynthesis. |
| 外观 (Physical appearance) |
Liquid |
| 浓度(Concentration) | ~1mg/ml |
| 纯度(Purity) | ≥95% by SDS-PAGE |
| 储存液(Storage buffer) | 10mM HEPES (pH7.4), 25mM KCl, 5mM DTT, 10% Glycerol. |
本产品经SDS-PAGE电泳检测蛋白纯度和分子量请参考图1。
图1.碧云天Recombinant Human CMPK1 (His-Tag) (P2523)的SDS-PAGE电泳检测效果图。本蛋白经BeyoGel™ Elite PAGE预制胶(Bis-Tris, 4-15%, 10孔) (P0856)电泳，上样缓冲液为BeyoGel™ LDS Sample Buffer (4X) (P0731)，Marker为BeyoColor™彩色预染蛋白分子量标准(6.5-270kD) (P0071/P0072)，并经BeyoBlue™考马斯亮蓝超快染色液(P0017F)染色。实际结果会因产品批次、实验条件、检测仪器等的不同而存在差异，图中效果仅供参考。
包装清单：| 产品编号 | 产品名称 | 包装 |
| P2523-10μg | rhCMPK1 (His-Tag) (1mg/ml) | 10μl |
| P2523-50μg | rhCMPK1 (His-Tag) (1mg/ml) | 50μl |
| P2523-200μg | rhCMPK1 (His-Tag) (1mg/ml) | 200μl |
| P2523-1mg | rhCMPK1 (His-Tag) (1mg/ml) | 1ml |
| － | 说明书 | 1份 |
-20ºC保存，一年有效。-80ºC保存，可以保存更长时间。
注意事项：由于蛋白的每次冻融均会引起部分失活，所以首次配制成相应浓度的储存液后，须分装后-20ºC或更低温度冻存，尽量避免反复冻融。
本产品仅限于专业人员的科学研究用，不得用于临床诊断或治疗，不得用于食品或药品，不得存放于普通住宅内。
为了您的安全和健康，请穿实验服并戴一次性手套操作。
| 产品编号 | 产品名称 | 包装 |
| P2520 | Recombinant Active Human BACE1 (His-Tag) | 10μg/100μg/1mg |
| P2523 | Recombinant Human CMPK1 (His-Tag) | 10μg/50μg/200μg/1mg |
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